Chief Medical Officer / SVP Clinical Development (m/f/d)
SJP Biotec GmbH (Job via XING.com)
📍 Zürich
📑 Unbefristeter Vertrag
⏱️ Vollzeit
👨🏻💼 Führungskräfte & Management
💼 Professional
Branche
Pharmaindustrie
Aufgaben
- Serve as the clinical face of the company; translate and deliver key directives from the board and senior management
- Lead and manage all clinical development activities across the SJP portfolio
- Design Phase 2 and 3 clinical protocols and oversee CTA/IND submissions to BfArM, FDA, and EMA
- Develop and implement biomarker-driven patient selection strategies
- Build and manage relationships with leading academic and clinical sites across Germany, the EU, and the US
- Oversee Investigator Initiated Trials and partnerships, providing scientific leadership and interactions as required
- Lead regulatory strategy, including Fast Track, Breakthrough Therapy and accelerated approval pathways
- Support pharmaceutical partnering activities: prepare clinical data packages and respond to due diligence for licensing/out-licensing
- Build out the clinical development and operations function, recruit CRAs, medical monitors, and data management staff
- Present clinical data at major oncology congresses and to key opinion leaders
- Interact with potential investors and financial institutions to raise capital when needed
Hard skills
- MD, with specialization in medical oncology and hematology
- 10+ years of experience in oncology clinical development within pharma, biotech, or CRO settings with hands-on clinical trial leadership
- Demonstrated track record of successful IND/CTA submissions
- Leadership of interactions with FDA and/or EMA
- Experience with biomarker-driven trial design and companion diagnostic development
- Expertise in breast cancer, NSCLC, and KRAS-mutant tumor biology
- Strong understanding of the competitive treatment landscape in clinical oncology
- Proven ability to manage investigator-initiated trials and academic site partnerships
- Strong scientific publication and/or congress presentation record in clinical oncology
- Excellent presentation skills and emphasis on teamwork and leading a team of experts
- Highly desired: experience with RAS/KRAS biology, MAPK pathway inhibitors, or translation-pathway therapeutics
- Highly desired: PhD in associated area of cancer biology
- Highly desired: experience with basket trial design and multi-cohort oncology studies
- Highly desired: background in immuno-oncology combinations and checkpoint inhibitor resistance
- Highly desired: prior involvement in pharma partnering or licensing due diligence
- Highly desired: working knowledge of German regulatory frameworks and international GCP/ICH guidelines
- Highly desired: established professional network at leading cancer centres
Benefits
- Location: Zurich, Switzerland; flexible remote/hybrid arrangements
- Regular travel to EU and US clinical sites required
- Contract type: Full-time, VP/C-suite equivalent reporting to the Managing Director
- Competitive salary commensurate with industry norms and annual performance-related bonus
- Start date: As soon as possible
- Confidential handling of applications; discretion regarding current employer and references
- Equal-opportunity employer committed to diversity and inclusion
