PhD student (f/m/x) for the study of microbial regulation of colorectal cancer development

Universitätsmedizin Greifswald KöR (Job via XING.com)

📍 Greifswald

🔖 Praktikum

🎓 Werkstudent

📑 Unbefristeter Vertrag

⏱️ Teilzeit

🔬 Wissenschaft & Forschung

💼 Entry

Wissenschaft & Forschung

Design and perform experiments using mouse models of orthotopic colorectal cancer, including gnotobiotic mice
Work with primary human and murine intestinal organoids in 2D and 3D co-cultures to study host–microbial interactions
Perform and analyse scRNA/snRNA and spatial RNA sequencing
Conduct metagenomic sequencing and metabolomic studies to characterise microbiota and metabolites
Dissect microbiota-dependent pathways that regulate CRC progression, metastasis and age-dependent effects
Identify druggable host–microbial interactions that promote CRC progression
Collaborate in a cross-disciplinary research consortium and contribute to publications and presentations

Master's degree (or equivalent) in Immunology, Microbiology, Molecular Biology, Biotechnology, Animal Science or related biological sciences
Ideally: experience working with mice (in vivo models)
Experience or basic skills in microbiology and cell culture techniques (organoids)
Familiarity or willingness to work with sequencing and omics approaches (scRNA/snRNA, spatial RNA-seq, metagenomics, metabolomics) is advantageous
Open-minded, active, team player
Good command of English (oral and written)

Part-time position (65%) with fixed-term contract for 3 years (possibility of extension)
Payment according to TV-L (65% of E13)
Company pension schemes and employee discounts
Regular training and professional development programs
Interdisciplinary collaboration and research support (infrastructure and resources)
Flexible working hours and health promotion programs (cooperation with Hansefit GmbH)
Family office support for accommodation and work–life balance
Located in Greifswald — attractive university town near the Baltic Sea

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